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crease in colony formation in soft agar compared with control mimics. Conversely, silencing of miR-7 in HBL-100 cells increased colony formation in soft agar. These outcomes indicated that miR-7 inhibits breast cancer cells monolayer proliferation and anchorage independent development in vitro. We also cultured the cells in three-dimensional Matrigel; expanding cells in or on gels which revealed
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