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Ients with advanced ovarian carcinoma? Am J Obstet Gynecol. 2014;211(3):231. e231?39. 3. Martin LP, Sill M, Shahin MS, Powell M, DiSilvestro P, Landrum LM, et al. A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol. 2014;132(3):526?0. 4. Mats
Is still the most lethal gynecologic malignancy worldwide. Although most ovarian carcinoma cells are initially sensitive to chemotherapy, there is always a small population cells that always survives and initiates new tumors which causes recurrence [31]. The verification of tumor heterogeneity further enhances the hypothesis of CSCs. Compelling evidence has shown that ovarian carcinomas with enri
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Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cl
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N the p53 DBD but additional parts of the four domain cassette tend to cluster, suggesting that more conserved functional sequence motifs may indeed remain within their p53 DBD, compared to the others. Further, cnidarian clusters with the multidomain proteins suggesting that they too may have more of the original functionality left. Noteworthy is that the annelid and mollusc clade, containing L.
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